Image Registration of Structural and Physiological MR Images of Abnormal Anatomy

Andreas Mang, Oscar Camara, Gisele Brasil Caseiras, William R. Crum, Julia A. Schnabel, Thorsten M. Buzug, John Thornton, H. Rolf Jäger, David J. Hawkes


This study applies image registration techniques to combine functional and structural information derived from multi-modal magnetic resonance imaging in patients diagnosed with brain gliomas. The images vary substantially in resolution, signal-to-noise ratio, information content and field of view and therefore pose a challenging registration problem. Specific protocols have been designed for each registration task, with careful selection of critical parameters and appropriate pre-processing. In addition, we have developed a visual assessment protocol to evaluate the accuracy of the proposed methods. Preliminary results suggest that registrations errors are below the functional image resolutions, thus achieving sub-voxel accuracy.
Original languageEnglish
Title of host publicationAdvances in Medical Engineering
EditorsThorsten M. Buzug, Dietrich Holz, Jens Bongartz, Matthias Kohl-Bareis, Ulrich Hartmann, Simone Weber
Number of pages6
Place of PublicationBerlin, Heidelberg
PublisherSpringer Berlin Heidelberg
Publication date01.01.2007
ISBN (Print)978-3-540-68763-4
ISBN (Electronic)978-3-540-68764-1
Publication statusPublished - 01.01.2007


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