Abstract
Transcription is an energy-consuming process. From an economical view it is reasonable that not all genes are transcribed simultaneously in one cell. Indeed, most genes are transcribed only when a specific gene product is needed. Regulation of gene expression is mainly achieved by the coordinate interplay of different transcription factors (TFs) and transcriptional coactivators with DNA-dependent RNA-polymerases. To gain spatial and temporal control in this process, TFs have to fulfill two prerequisites: sequence specificity and inducibility.
Original language | English |
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Title of host publication | Oxygen Sensing : Responses and Adaption to Hypoxia |
Number of pages | 16 |
Publisher | CRC Press |
Publication date | 01.01.2003 |
Pages | 93-108 |
ISBN (Print) | 9780824709600 |
ISBN (Electronic) | 9780824748456 |
Publication status | Published - 01.01.2003 |
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)