Hypersalivation - Aktualisierung der S2k-Leitlinie (AWMF) in gekürzter Darstellung

Translated title of the contribution: Hypersalivation - Update of the S2k guideline (AWMF) in short form

Armin Steffen*, Wolfgang Jost, Tobias Bäumer, Dirk Beutner, Sabine Degenkolb-Weyers, Martin Gro, Maria Grosheva, Samer Hakim, Kai G. Kahl, Rainer Laskawi, Rebekka Lencer, Jan Löhler, Thekla Meyners, Saskia Rohrbach-Volland, Rainer Schönweiler, Sara Christina Schröder, Sebastian Schröder, Heidrun Schröter-Morasch, Maria Schuster, Susanne SteinlechnerRoland Urban, Orlando Guntinas-Lichius

*Corresponding author for this work
1 Citation (Scopus)


Hypersalivation describes a relatively excessive salivary flow, which wets the patient himself and his surroundings. It may result because of insufficient oro-motor function, dysphagia, decreased central control and coordination. This update presents recent changes and innovation in the treatment of hypersalivation. Multidisciplinary diagnostic and treatment evaluation is recommended already at early stage and focus on dysphagia, saliva aspiration, and oro-motor deficiencies. Clinical screening tools and diagnostics such as fiberoptic endoscopic evaluation of swallowing generate important data on therapy selection and control. Many cases profit from swallowing therapy programmes in order to activate compensation mechanisms as long compliances is given. In children with hypotonic oral muscles, oral stimulation plates can induce a relevant symptom release because of the improved lip closure. The pharmacologic treatment improved for pediatric cases as glycopyrrolate fluid solution (Sialanar ®) is now indicated for hypersalivation within the E. U. The injection of botulinum toxin into the salivary glands has shown safe and effective results with long lasting saliva reduction. Here, a phase III trial is completed for Incobotulinum toxin A and, in the U. S., is indicated for the treatment of adult patients with chronic hypersalivation. Surgical treatment should be reserved for isolated cases. External radiation is judged as a safe and effective therapy when using modern 3 D techniques to minimize tissue damage. Therapy effects and symptom severity has to be followed, especially in cases with underlying neurodegenerative disease.

Translated title of the contributionHypersalivation - Update of the S2k guideline (AWMF) in short form
Original languageGerman
JournalLaryngo- Rhino- Otologie
Issue number6
Pages (from-to)388-397
Number of pages10
Publication statusPublished - 05.06.2019


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