TY - JOUR
T1 - Hyperacute rejection of a living unrelated kidney graft
AU - Tittelbach-Helmrich, Dietlind
AU - Bausch, Dirk
AU - Drognitz, Oliver
AU - Goebel, Heike
AU - Schulz-Huotari, Christian
AU - Kramer-Zucker, Albrecht
AU - Hopt, Ulrich Theodor
AU - Pisarski, Przemyslaw
AU - Keck, Tobias
N1 - Publisher Copyright:
Copyright © 2014 Dietlind Tittelbach-Helmrich et al.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2014/9/17
Y1 - 2014/9/17
N2 - We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation, resulted positive. During surgery no abnormalities occurred. Four hours after the transplantation diuresis suddenly decreased. In an immediately performed relaparotomy the transplanted kidney showed signs of hyperacute rejection and had to be removed. Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. We recommend examining more closely recipients of second allografts, considering not only a positive T-cell crossmatch but also a positive B-cell crossmatch as exclusion criteria for transplantation.
AB - We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation, resulted positive. During surgery no abnormalities occurred. Four hours after the transplantation diuresis suddenly decreased. In an immediately performed relaparotomy the transplanted kidney showed signs of hyperacute rejection and had to be removed. Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. We recommend examining more closely recipients of second allografts, considering not only a positive T-cell crossmatch but also a positive B-cell crossmatch as exclusion criteria for transplantation.
UR - http://www.scopus.com/inward/record.url?scp=85032638033&partnerID=8YFLogxK
U2 - 10.1155/2014/613641
DO - 10.1155/2014/613641
M3 - Journal articles
AN - SCOPUS:85032638033
SN - 1687-9627
VL - 2014
JO - Case Reports in Medicine
JF - Case Reports in Medicine
M1 - 613641
ER -