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Human cerebral circuitry related to cardiac control: A neuroimaging meta-analysis

Estefanía Ruiz Vargas, Peter Sörös, J. Kevin Shoemaker*, Vladimir Hachinski

*Corresponding author for this work

Abstract

Serious arrhythmias often follow stroke, highlighting the important role that the cerebral cortex has in neural regulation of the heart. Neuroimaging studies reveal patterns of activation associated with autonomic cardiovascular responses. Using the activation likelihood estimation, a meta-analysis was performed to identify cortical activation patterns related to heart rate and heart rate variability across studies that used differing stimuli of cardiovascular arousal. Consistent associations with heart rate and heart rate variability were observed in the anterior cingulate, amygdala, insula, and prefrontal cortex, among others. Also, evidence is provided of insular lateralization associated with autonomic cardiac responses. Ann Neurol 2016;79:709-716

Original languageEnglish
JournalAnnals of Neurology
Volume79
Issue number5
Pages (from-to)709-716
Number of pages8
ISSN0364-5134
DOIs
Publication statusPublished - 01.05.2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 10 - Reduced Inequalities
    SDG 10 Reduced Inequalities

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