How much does AMH really vary in normal women?

Antonio La Marca*, Valentina Grisendi, Georg Griesinger

*Corresponding author for this work
26 Citations (Scopus)


Anti-Mullerian Hormone (AMH) is an ovarian hormone expressed in growing follicles that have undergone recruitment from the primordial follicle pool but have not yet been selected for dominance. It is considered an accurate marker of ovarian reserve, able to reflect the size of the ovarian follicular pool of a woman of reproductive age. In comparison to other hormonal biomarkers such as serum FSH, low intra- and intermenstrual cycle variability have been proposed for AMH. This review summarizes the knowledge regarding within-subject variability, with particular attention on AMH intracycle variability. Moreover the impact of ethnicity, body mass index, and smoking behaviour on AMH interindividual variability will be reviewed. Finally changes in AMH serum levels in two conditions of ovarian quiescence, namely contraceptives use and pregnancy, will be discussed. The present review aims at guiding researchers and clinicians in interpreting AMH values and fluctuations in various research and clinical scenarios.

Original languageEnglish
Article number959487
JournalInternational Journal of Endocrinology
Pages (from-to)959487
Publication statusPublished - 16.12.2013


Dive into the research topics of 'How much does AMH really vary in normal women?'. Together they form a unique fingerprint.

Cite this