TY - JOUR
T1 - Histopathological features and ann arbor stage in periocular lymphoma
AU - Zschoche, Marco
AU - Zimpfer, Annette
AU - Scheef, Björn O.
AU - Jünemann, Anselm M.
AU - Guthoff, Rudolf F.
AU - Junghanss, Christian
AU - Hildebrandt, Guido
AU - Emmert, Steffen
AU - Erbersdobler, Andreas
AU - Kundt, Günther
AU - Kakkassery, Vinodh
N1 - Funding Information:
S.E. is supported by the European Social Fund, reference: ESF/14-BM-A55-0001/18, and the Ministry of Education, Science and Culture of Mecklenburg-West Pomerania, Germany as well as by the Damp Foundation.
Publisher Copyright:
© 2020 International Institute of Anticancer Research. All rights reserved.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2020/8
Y1 - 2020/8
N2 - Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large Bcell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.
AB - Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL). Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018. Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large Bcell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048). Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.
UR - http://www.scopus.com/inward/record.url?scp=85087384389&partnerID=8YFLogxK
U2 - 10.21873/invivo.11993
DO - 10.21873/invivo.11993
M3 - Journal articles
C2 - 32606168
AN - SCOPUS:85087384389
SN - 0258-851X
VL - 34
SP - 1965
EP - 1974
JO - In Vivo
JF - In Vivo
IS - 4
ER -
