Heartbeat OCT and Motion-Free 3D in Vivo Coronary Artery Microscopy

Tianshi Wang, Tom Pfeiffer, Evelyn Regar, Wolfgang Wieser, Heleen Van Beusekom, Charles T. Lancee, Geert Springeling, Ilona Krabbendam-Peters, Antonius F.W. Van Der Steen*, Robert Huber, Gijs Van Soest

*Corresponding author for this work
5 Citations (Scopus)


Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of coronary artery pathologies and interventions (1). In contrast to the cross-sectional view, longitudinal sections and 3-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements (2). We developed Heartbeat OCT, a new OCT method that achieves up to 4,000 frames/s imaging speed for isotropically sampled volume datasets acquired within the diastolic phase of 1 cardiac cycle to restore 3D IV-OCT image fidelity. In this research letter, we present the first in vivo data acquired with this new experimental technology.
Original languageEnglish
JournalJACC: Cardiovascular Imaging
Issue number5
Pages (from-to)622-623
Number of pages2
Publication statusPublished - 01.05.2016


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