Hat COVID-19 das Spektrum der Herzrhythmusstörungen und die Häufigkeit des plötzlichen Herztods verändert?

Translated title of the contribution: Has COVID-19 changed the spectrum of arrhythmias and the incidence of sudden cardiac death?

Karl Heinz Kuck*, Michael Schlüter, Julia Vogler, Christian Hendrik Heeger, Roland Richard Tilz

*Corresponding author for this work

Abstract

Arrhythmic manifestations of COVID-19 include atrial arrhythmias such as atrial fibrillation or atrial flutter, sinus node dysfunction, atrioventricular conduction abnormalities, ventricular tachyarrhythmias, sudden cardiac arrest, and cardiovascular dysautonomias including the so-called long COVID syndrome. Various pathophysiological mechanisms have been implicated, such as direct viral invasion, hypoxemia, local and systemic inflammation, changes in ion channel physiology, immune activation, and autonomic dysregulation. The development of atrial or ventricular arrhythmias in hospitalized COVID-19 patients has been shown to portend a higher risk of in-hospital death. Management of these arrhythmias should be based on published evidence-based guidelines, with special consideration of the acuity of COVID-19 infection, concomitant use of antimicrobial and anti-inflammatory drugs, and the transient nature of some rhythm disorders. In view of new SARS-CoV‑2 variants that may evolve, the development and use of newer antiviral and immunomodulator drugs, and the increasing adoption of vaccination, clinicians must remain vigilant for other arrhythmic manifestations that may occur in association with this novel but potentially deadly disease.

Translated title of the contributionHas COVID-19 changed the spectrum of arrhythmias and the incidence of sudden cardiac death?
Original languageGerman
JournalHerz
Volume48
Issue number3
Pages (from-to)212-217
Number of pages6
ISSN0340-9937
DOIs
Publication statusPublished - 06.2023

Research Areas and Centers

  • Centers: Cardiological Center Luebeck (UHZL)

DFG Research Classification Scheme

  • 205-12 Cardiology, Angiology

Coronavirus related work

  • Research on SARS-CoV-2 / COVID-19

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