TY - JOUR
T1 - GLUT12-A promising new target for the treatment of insulin resistance in obesity and type 2 diabetes
AU - Astiz, Mariana
AU - Oster, Henrik
PY - 2019/8/1
Y1 - 2019/8/1
N2 - In this issue of Acta Physiologica, Gil-Iturbe et al. show how activity of the facilitative glucose transporter 12 (GLUT12, SLC2A12) in adipose tissues is regulated by metabolic signals such as insulin, leptin, adiponectin, tumour necrosis factor alpha (TNFα), and hypoxia. Using both in-vitro and in-vivo approaches the authors compare the hormonal modulation of GLUT12 expression and activity to that of GLUT4, the main insulin sensitive transporter responsible for glucose uptake. This article is protected by copyright. All rights reserved.
AB - In this issue of Acta Physiologica, Gil-Iturbe et al. show how activity of the facilitative glucose transporter 12 (GLUT12, SLC2A12) in adipose tissues is regulated by metabolic signals such as insulin, leptin, adiponectin, tumour necrosis factor alpha (TNFα), and hypoxia. Using both in-vitro and in-vivo approaches the authors compare the hormonal modulation of GLUT12 expression and activity to that of GLUT4, the main insulin sensitive transporter responsible for glucose uptake. This article is protected by copyright. All rights reserved.
UR - http://www.scopus.com/inward/record.url?scp=85068607350&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/glut12a-promising-new-target-treatment-insulin-resistance-obesity-type-2-diabetes
U2 - 10.1111/apha.13329
DO - 10.1111/apha.13329
M3 - Journal articles
C2 - 31179587
SN - 1748-1708
VL - 226
SP - e13329
JO - Acta Physiologica
JF - Acta Physiologica
IS - 4
M1 - e13329
ER -
