Glandular stem cells are a promising source for much more than β-cell replacement

Daniel H. Rapoport, Sandra Danner, Charli Kruse*

*Corresponding author for this work
3 Citations (Scopus)


Glandular stem cells (GSCs) can be obtained from exocrine glands such as pancreas or salivary glands using well-established cell culturing methods. The resulting cell populations are characterized by a high proliferative capacity and an unusually high plasticity. Cells from pancreas have been demonstrated to differentiate into a multitude of cell types and even into oocyte-like cells. It has been found that the preparation method for GSCs can be applied to many vertebrates, including fishes and birds. Since the cells are excellently cryopreservable, this finding has been utilized to establish a new stem cell bank for preserving living cells of rare and wild animals. Apart from these advances, this mini-review also points out that GSCs from pancreas must not be confused with β-cell progenitors but constitute a distinct cell type.

Original languageEnglish
JournalAnnals of Anatomy
Issue number1
Pages (from-to)62-69
Number of pages8
Publication statusPublished - 01.2009

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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