Geschlechtsspezifische Unterschiede in uro-onkologischen Studien

Marie Christine Roesch; Lea Sophie Lütje; Nils Gilbert; Axel Stuart Merseburger; Daniar Osmonov

doi:10.1055/a-2510-9757

Geschlechtsspezifische Unterschiede in uro-onkologischen Studien

Translated title of the contribution: Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology

Marie Christine Roesch^*, Lea Sophie Lütje, Nils Gilbert, Axel Stuart Merseburger, Daniar Osmonov

^*Corresponding author for this work

Abstract

Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.

Translated title of the contribution	Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology
Original language	German
Journal	Aktuelle Urologie
Volume	56
Issue number	2
Pages (from-to)	131-134
Number of pages	4
ISSN	0001-7868
DOIs	https://doi.org/10.1055/a-2510-9757
Publication status	Published - 28.01.2025

Research Areas and Centers

Research Area: Luebeck Integrated Oncology Network (LION)

DFG Research Classification Scheme

2.22-23 Reproductive Medicine, Urology
2.22-14 Hematology, Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/a-2510-9757

Cite this

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title = "Geschlechtsspezifische Unterschiede in uro-onkologischen Studien",

abstract = "Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.",

author = "Roesch, {Marie Christine} and L{\"u}tje, {Lea Sophie} and Nils Gilbert and Merseburger, {Axel Stuart} and Daniar Osmonov",

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doi = "10.1055/a-2510-9757",

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AU - Roesch, Marie Christine

AU - Lütje, Lea Sophie

AU - Gilbert, Nils

AU - Merseburger, Axel Stuart

AU - Osmonov, Daniar

PY - 2025/1/28

Y1 - 2025/1/28

N2 - Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.

AB - Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.

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EP - 134

JO - Aktuelle Urologie

JF - Aktuelle Urologie

IS - 2

ER -

Geschlechtsspezifische Unterschiede in uro-onkologischen Studien

Abstract

Research Areas and Centers

DFG Research Classification Scheme

UN SDGs

Access to Document

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