Genetik ovarieller störungen

Translated title of the contribution: The genetics of ovarian disturbances

A. Schröer*, P. H. Vogt, G. Griesinger, D. Fischer, K. Diedrich, T. Strowitzki

*Corresponding author for this work


Ovarian failure can result from several genetic mechanisms; X chromosomal abnormalities, autosomal recessive genes causing various types of XX gonadal dysgenesis, and autosomal dominant genes. Ovarian failure in patients can appear without any other clinical sign or as part of a syndrome. Failure of sex determination is common in patients with large chromosomal abnormalities, such as trisomies or monosomies. Conditions such as premature ovarian failure or polycystic ovary syndrome are likely to be heterogeneous clinical disorders due to complex genetic networks controlling human folliculogenesis.

Translated title of the contributionThe genetics of ovarian disturbances
Original languageGerman
JournalGynakologische Endokrinologie
Issue number1
Pages (from-to)5-12
Number of pages8
Publication statusPublished - 02.2007


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