Genetics of male subfertility: Consequences for the clinical work-up

Wolfgang Küpker*, Eberhard Schwinger, Olaf Hiort, Michael Ludwig, Nikos Nikolettos, Peter N. Schlegel, Klaus Diedrich

*Corresponding author for this work
31 Citations (Scopus)


Major principles of genetic failures, chromosomal alterations and the most common syndromes associated with male subfertility should be taken into account before medical therapy and sophisticated techniques of assisted fertilization are applied to help a couple conceive. This review addresses the most common genetic reasons for male subfertility or infertility with special regard to the importance for the clinical work-up in daily routine and the potential risks for the conceptus.

Original languageEnglish
JournalHuman Reproduction
Issue numberSUPPL. 1
Pages (from-to)24-37
Number of pages14
Publication statusPublished - 1999


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