Genetic determinants controlling lipid deposits in different wild type strains of zebrafish (Danio rerio)

K. Vishnolia, K. Tarhbalouti, P. Ciba, C. Kruse, Z. Aherrahrou, J. Erdmann

Abstract

Objectives: Zebrafish ( Danio rerio) has been established as a brilliant model to study dyslipidemia or atherosclerosis due to the remarkable similarities with humans in lipid and lipoprotein metabolism. In contrast to mice, zebrafish show lipoprotein oxidation and dyslipidemia after feeding with a high cholesterol diet for as short as 15 day’s time period, even without any genetic intervention.
Original languageEnglish
JournalAtherosclerosis
Volume252
Pages (from-to)70-71
Number of pages2
ISSN0021-9150
DOIs
Publication statusPublished - 01.09.2016

Research Areas and Centers

  • Research Area: Medical Genetics

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