Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Heike Bickeböller; Julia N. Bailey; Joseph Beyene; Rita M. Cantor; Heather J. Cordell; Robert C. Culverhouse; Corinne D. Engelman; David W. Fardo; Saurabh Ghosh; Inke R. König; Justo Lorenzo Bermejo; Phillip E. Melton; Stephanie A. Santorico; Glen A. Satten; Lei Sun; Nathan L. Tintle; Andreas Ziegler; Jean W. MacCluer; Laura Almasy

doi:10.1186/1753-6561-8-S1-S1

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Heike Bickeböller^*, Julia N. Bailey, Joseph Beyene, Rita M. Cantor, Heather J. Cordell, Robert C. Culverhouse, Corinne D. Engelman, David W. Fardo, Saurabh Ghosh, Inke R. König, Justo Lorenzo Bermejo, Phillip E. Melton, Stephanie A. Santorico, Glen A. Satten, Lei Sun, Nathan L. Tintle, Andreas Ziegler, Jean W. MacCluer, Laura Almasy

^*Corresponding author for this work

Institute of Medical Biometry and Statistic

12 Citations (Scopus)

Abstract

Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.

Original language	English
Article number	S1
Journal	BMC Proceedings
Volume	8
ISSN	1753-6561
DOIs	https://doi.org/10.1186/1753-6561-8-S1-S1
Publication status	Published - 17.06.2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/1753-6561-8-S1-S1

Cite this

Bickeböller, H., Bailey, J. N., Beyene, J., Cantor, R. M., Cordell, H. J., Culverhouse, R. C., Engelman, C. D., Fardo, D. W., Ghosh, S., König, I. R., Lorenzo Bermejo, J., Melton, P. E., Santorico, S. A., Satten, G. A., Sun, L., Tintle, N. L., Ziegler, A., MacCluer, J. W., & Almasy, L. (2014). Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees. BMC Proceedings, 8, Article S1. https://doi.org/10.1186/1753-6561-8-S1-S1

@article{17ec61a6c6bc4398ba8add3e1da822a0,

title = "Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees",

abstract = "Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.",

author = "Heike Bickeb{\"o}ller and Bailey, {Julia N.} and Joseph Beyene and Cantor, {Rita M.} and Cordell, {Heather J.} and Culverhouse, {Robert C.} and Engelman, {Corinne D.} and Fardo, {David W.} and Saurabh Ghosh and K{\"o}nig, {Inke R.} and {Lorenzo Bermejo}, Justo and Melton, {Phillip E.} and Santorico, {Stephanie A.} and Satten, {Glen A.} and Lei Sun and Tintle, {Nathan L.} and Andreas Ziegler and MacCluer, {Jean W.} and Laura Almasy",

note = "Publisher Copyright: {\textcopyright} 2014 Bickeb{\"o}ller et al.; licensee BioMed Central Ltd.",

year = "2014",

month = jun,

day = "17",

doi = "10.1186/1753-6561-8-S1-S1",

language = "English",

volume = "8",

journal = "BMC Proceedings",

issn = "1753-6561",

}

Bickeböller, H, Bailey, JN, Beyene, J, Cantor, RM, Cordell, HJ, Culverhouse, RC, Engelman, CD, Fardo, DW, Ghosh, S, König, IR, Lorenzo Bermejo, J, Melton, PE, Santorico, SA, Satten, GA, Sun, L, Tintle, NL, Ziegler, A, MacCluer, JW & Almasy, L 2014, 'Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees', BMC Proceedings, vol. 8, S1. https://doi.org/10.1186/1753-6561-8-S1-S1

TY - JOUR

T1 - Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

AU - Bickeböller, Heike

AU - Bailey, Julia N.

AU - Beyene, Joseph

AU - Cantor, Rita M.

AU - Cordell, Heather J.

AU - Culverhouse, Robert C.

AU - Engelman, Corinne D.

AU - Fardo, David W.

AU - Ghosh, Saurabh

AU - König, Inke R.

AU - Lorenzo Bermejo, Justo

AU - Melton, Phillip E.

AU - Santorico, Stephanie A.

AU - Satten, Glen A.

AU - Sun, Lei

AU - Tintle, Nathan L.

AU - Ziegler, Andreas

AU - MacCluer, Jean W.

AU - Almasy, Laura

PY - 2014/6/17

Y1 - 2014/6/17

N2 - Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.

AB - Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.

UR - http://www.scopus.com/inward/record.url?scp=85018193159&partnerID=8YFLogxK

U2 - 10.1186/1753-6561-8-S1-S1

DO - 10.1186/1753-6561-8-S1-S1

M3 - Journal articles

AN - SCOPUS:85018193159

SN - 1753-6561

VL - 8

JO - BMC Proceedings

JF - BMC Proceedings

M1 - S1

ER -

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this