Fully differential low noise amplifier for MPI/MPS

A. Malhotra; H. Schwegmann; J. Schumacher; X. Chen; T. M. Buzug

doi:10.18416/IJMPI.2020.2009006

Fully differential low noise amplifier for MPI/MPS

A. Malhotra^*, H. Schwegmann, J. Schumacher, X. Chen, T. M. Buzug

^*Corresponding author for this work

Institute of Medical Engineering

Abstract

Magnetic particle imaging (MPI) is a novel tomographic imaging modality, which uses static and dynamic magnetic fields to measure the magnetic response generated by superparamagnetic iron oxide nanoparticles (SPIONs). For the characterization of the SPIONs magnetic particle spectroscopy (MPS) is used. In the current research, a low noise amplifier (LNA) suitable for MPI and MPS is presented. LNAs play a significant role in the receive chain of MPI and MPS systems by amplifying the signals from the nanoparticles while keeping the noise induced through its own circuitry minimal. The LNA is based on a fully differential amplifier (FDA) in a summing configuration to reduce noise. The input voltage noise of the prototyped LNAwith a receive coil and a 50 Ω resistance in a bandwidth of 200-600 kHz is 300 pV/ Hz (NF = 14.05) and 1.76 nV/ Hz (NF = 11.93) respectively.

Original language	English
Article number	2009006
Journal	International Journal on Magnetic Particle Imaging
Volume	6
Issue number	2
Pages (from-to)	1-3
Number of pages	3
ISSN	2365-9033
DOIs	https://doi.org/10.18416/IJMPI.2020.2009006
Publication status	Published - 02.09.2020

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title = "Fully differential low noise amplifier for MPI/MPS",

abstract = "Magnetic particle imaging (MPI) is a novel tomographic imaging modality, which uses static and dynamic magnetic fields to measure the magnetic response generated by superparamagnetic iron oxide nanoparticles (SPIONs). For the characterization of the SPIONs magnetic particle spectroscopy (MPS) is used. In the current research, a low noise amplifier (LNA) suitable for MPI and MPS is presented. LNAs play a significant role in the receive chain of MPI and MPS systems by amplifying the signals from the nanoparticles while keeping the noise induced through its own circuitry minimal. The LNA is based on a fully differential amplifier (FDA) in a summing configuration to reduce noise. The input voltage noise of the prototyped LNAwith a receive coil and a 50 Ω resistance in a bandwidth of 200-600 kHz is 300 pV/ Hz (NF = 14.05) and 1.76 nV/ Hz (NF = 11.93) respectively.",

author = "A. Malhotra and H. Schwegmann and J. Schumacher and X. Chen and Buzug, {T. M.}",

note = "Funding Information: We gratefully acknowledge the financial support from the Deutsche Forschungsgemeinschaft, Germany (DFG, grant numbers BU 1436/9-1). Publisher Copyright: {\textcopyright} 2020 Infinite Science Publishing. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

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AU - Malhotra, A.

AU - Schwegmann, H.

AU - Schumacher, J.

AU - Chen, X.

AU - Buzug, T. M.

N1 - Funding Information: We gratefully acknowledge the financial support from the Deutsche Forschungsgemeinschaft, Germany (DFG, grant numbers BU 1436/9-1). Publisher Copyright: © 2020 Infinite Science Publishing. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/9/2

Y1 - 2020/9/2

N2 - Magnetic particle imaging (MPI) is a novel tomographic imaging modality, which uses static and dynamic magnetic fields to measure the magnetic response generated by superparamagnetic iron oxide nanoparticles (SPIONs). For the characterization of the SPIONs magnetic particle spectroscopy (MPS) is used. In the current research, a low noise amplifier (LNA) suitable for MPI and MPS is presented. LNAs play a significant role in the receive chain of MPI and MPS systems by amplifying the signals from the nanoparticles while keeping the noise induced through its own circuitry minimal. The LNA is based on a fully differential amplifier (FDA) in a summing configuration to reduce noise. The input voltage noise of the prototyped LNAwith a receive coil and a 50 Ω resistance in a bandwidth of 200-600 kHz is 300 pV/ Hz (NF = 14.05) and 1.76 nV/ Hz (NF = 11.93) respectively.

AB - Magnetic particle imaging (MPI) is a novel tomographic imaging modality, which uses static and dynamic magnetic fields to measure the magnetic response generated by superparamagnetic iron oxide nanoparticles (SPIONs). For the characterization of the SPIONs magnetic particle spectroscopy (MPS) is used. In the current research, a low noise amplifier (LNA) suitable for MPI and MPS is presented. LNAs play a significant role in the receive chain of MPI and MPS systems by amplifying the signals from the nanoparticles while keeping the noise induced through its own circuitry minimal. The LNA is based on a fully differential amplifier (FDA) in a summing configuration to reduce noise. The input voltage noise of the prototyped LNAwith a receive coil and a 50 Ω resistance in a bandwidth of 200-600 kHz is 300 pV/ Hz (NF = 14.05) and 1.76 nV/ Hz (NF = 11.93) respectively.

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M3 - Journal articles

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JO - International Journal on Magnetic Particle Imaging

JF - International Journal on Magnetic Particle Imaging

IS - 2

M1 - 2009006

ER -

Fully differential low noise amplifier for MPI/MPS

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