Frühdiagnose von vaskulitiden

Translated title of the contribution: Early diagnosis of vasculitides

B. Hellmich*, P. Lamprecht, P. M. Aries, W. L. Gross

*Corresponding author for this work
16 Citations (Scopus)


The often unspecific symptoms like myalgias, fever and weight loss at the onset of vasculitides are a frequent cause for a delay in diagnosis. Organspecific symptoms like hemoptysis, dyspnoea, epistaxis, edema and organ infarcts a present when organ dysfunction occurs as a result of vasculitis. Targeted serologic testing including antineutrophil cytoplasm antibodies (ANCA) and cryoglobulins allows early diagnosis of certain vasculitides. Modern imaging techniques like magnetic resonance imaging, computed tomography, positron-emission tomography and ultrasound are cornerstones for an early diagnosis as they allow the detection of subclinical disease and are helpful in the identification of a site for biopsy. Bioptic proof of vasculitis is still the gold standard for diagnosis. Functionally relevant damage caused by systemic inflammatory disorders can by reduced or sometimes avoided by early initiation of treatment. This requires a correct diagnosis is made as early as possible.

Translated title of the contributionEarly diagnosis of vasculitides
Original languageGerman
JournalZeitschrift fur Rheumatologie
Issue number8
Pages (from-to)538-546
Number of pages9
Publication statusPublished - 11.2005

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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