First Prompt Gamma Timing measurements with carbon ions

Sahar Ranjbar; Emanuele Data; Felix Mas Milian; Davide Bersani; Piergiorgio Cerello; Roberto Cirio; Veronica Ferrero; Mohammad Fadavi Mazinani; Simona Giordanengo; Mohammad Amin Hosseini; Elena Lombardo; Diango Manuel Montalvan-Olivares; Marco Pullia; Simone Savazzi; Roberto Sacchi; Anna Vignati; Julius Werner; Francesco Pennazio; Elisa Fiorina

doi:10.1109/NSS/MIC/RTSD57108.2024.10655573

First Prompt Gamma Timing measurements with carbon ions

Sahar Ranjbar, Emanuele Data, Felix Mas Milian, Davide Bersani, Piergiorgio Cerello, Roberto Cirio, Veronica Ferrero, Mohammad Fadavi Mazinani, Simona Giordanengo, Mohammad Amin Hosseini, Elena Lombardo, Diango Manuel Montalvan-Olivares, Marco Pullia, Simone Savazzi, Roberto Sacchi, Anna Vignati, Julius Werner, Francesco Pennazio, Elisa Fiorina

Institute of Medical Engineering

Abstract

The Prompt Gamma Timing (PGT) method provides the assessment of particle range by measuring the time of flight between the primary particle and PG detection. This non-invasive and real-time approach is a tool to monitor the therapy’s effectiveness and reduce uncertainties in treatment planning. We report the first PGT results obtained with carbon ion beams at the sub-clinical rate at the CNAO (Pavia, IT). The experimental setup relies on a silicon strip sensor to measure the transit time of the primaries and a detector based on a monolithic LaBr3-crystal coupled to a Silicon PhotoMultiplier matrix. Homogeneous and in-homogeneous phantoms have been irradiated with carbon ion beams of energy equal to $398 MeV / u$. The obtained results are promising, and further tests are foreseen to address clinical rates and prove the applicability of this approach to clinics.

Original language	Undefined/Unknown
Title of host publication	2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD)
Number of pages	1
Publication date	01.10.2024
Pages	1-1
DOIs	https://doi.org/10.1109/NSS/MIC/RTSD57108.2024.10655573
Publication status	Published - 01.10.2024

Research Areas and Centers

Academic Focus: Biomedical Engineering

DFG Research Classification Scheme

205-32 Medical Physics, Biomedical Engineering

Access to Document

10.1109/NSS/MIC/RTSD57108.2024.10655573

Cite this

Ranjbar, S., Data, E., Milian, F. M., Bersani, D., Cerello, P., Cirio, R., Ferrero, V., Mazinani, M. F., Giordanengo, S., Hosseini, M. A., Lombardo, E., Montalvan-Olivares, D. M., Pullia, M., Savazzi, S., Sacchi, R., Vignati, A., Werner, J., Pennazio, F., & Fiorina, E. (2024). First Prompt Gamma Timing measurements with carbon ions. In 2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD) (pp. 1-1) https://doi.org/10.1109/NSS/MIC/RTSD57108.2024.10655573

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abstract = "The Prompt Gamma Timing (PGT) method provides the assessment of particle range by measuring the time of flight between the primary particle and PG detection. This non-invasive and real-time approach is a tool to monitor the therapy{\textquoteright}s effectiveness and reduce uncertainties in treatment planning. We report the first PGT results obtained with carbon ion beams at the sub-clinical rate at the CNAO (Pavia, IT). The experimental setup relies on a silicon strip sensor to measure the transit time of the primaries and a detector based on a monolithic LaBr3-crystal coupled to a Silicon PhotoMultiplier matrix. Homogeneous and in-homogeneous phantoms have been irradiated with carbon ion beams of energy equal to $398 MeV / u$. The obtained results are promising, and further tests are foreseen to address clinical rates and prove the applicability of this approach to clinics.",

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Ranjbar, S, Data, E, Milian, FM, Bersani, D, Cerello, P, Cirio, R, Ferrero, V, Mazinani, MF, Giordanengo, S, Hosseini, MA, Lombardo, E, Montalvan-Olivares, DM, Pullia, M, Savazzi, S, Sacchi, R, Vignati, A, Werner, J, Pennazio, F & Fiorina, E 2024, First Prompt Gamma Timing measurements with carbon ions. in 2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD). pp. 1-1. https://doi.org/10.1109/NSS/MIC/RTSD57108.2024.10655573

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T1 - First Prompt Gamma Timing measurements with carbon ions

AU - Ranjbar, Sahar

AU - Data, Emanuele

AU - Milian, Felix Mas

AU - Bersani, Davide

AU - Cerello, Piergiorgio

AU - Cirio, Roberto

AU - Ferrero, Veronica

AU - Mazinani, Mohammad Fadavi

AU - Giordanengo, Simona

AU - Hosseini, Mohammad Amin

AU - Lombardo, Elena

AU - Montalvan-Olivares, Diango Manuel

AU - Pullia, Marco

AU - Savazzi, Simone

AU - Sacchi, Roberto

AU - Vignati, Anna

AU - Werner, Julius

AU - Pennazio, Francesco

AU - Fiorina, Elisa

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AB - The Prompt Gamma Timing (PGT) method provides the assessment of particle range by measuring the time of flight between the primary particle and PG detection. This non-invasive and real-time approach is a tool to monitor the therapy’s effectiveness and reduce uncertainties in treatment planning. We report the first PGT results obtained with carbon ion beams at the sub-clinical rate at the CNAO (Pavia, IT). The experimental setup relies on a silicon strip sensor to measure the transit time of the primaries and a detector based on a monolithic LaBr3-crystal coupled to a Silicon PhotoMultiplier matrix. Homogeneous and in-homogeneous phantoms have been irradiated with carbon ion beams of energy equal to $398 MeV / u$. The obtained results are promising, and further tests are foreseen to address clinical rates and prove the applicability of this approach to clinics.

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