TY - JOUR
T1 - First Dedicated Balloon Catheter for Magnetic Particle Imaging
AU - Ahlborg, Mandy
AU - Friedrich, Thomas
AU - Gottsche, Thorsten
AU - Scheitenberger, Vincent
AU - Linemann, Reinhard
AU - Wattenberg, Maximilian
AU - Buessen, Anne T.
AU - Knopp, Tobias
AU - Szwargulski, Patryk
AU - Kaul, Michael G.
AU - Salamon, Johannes
AU - Buzug, Thorsten M.
AU - Barkhausen, Jorg
AU - Wegner, Franz
N1 - Publisher Copyright:
© 1982-2012 IEEE.
PY - 2022/11/1
Y1 - 2022/11/1
N2 - Vascular interventions are a promising application of Magnetic Particle Imaging enabling a high spatial and temporal resolution without using ionizing radiation. The possibility to visualize the vessels as well as the devices, especially at the same time using multi-contrast approaches, enables a higher accuracy for diagnosis and treatment of vascular diseases. Different techniques to make devices MPI visible have been introduced so far, such as varnish markings or filling of balloons. However, all approaches include challenges for in vivo applications, such as the stability of the varnishing or the visibility of tracer filled balloons in deflated state. In this contribution, we present for the first time a balloon catheter that is molded from a granulate incorporating nanoparticles and can be visualized sufficiently in MPI. Computed tomography is used to show the homogeneous distribution of particles within the material. Safety measurements confirm that the incorporation of nanoparticles has no negative effect on the balloon. A dynamic experiment is performed to show that the inflation as well as deflation of the balloon can be imaged with MPI.
AB - Vascular interventions are a promising application of Magnetic Particle Imaging enabling a high spatial and temporal resolution without using ionizing radiation. The possibility to visualize the vessels as well as the devices, especially at the same time using multi-contrast approaches, enables a higher accuracy for diagnosis and treatment of vascular diseases. Different techniques to make devices MPI visible have been introduced so far, such as varnish markings or filling of balloons. However, all approaches include challenges for in vivo applications, such as the stability of the varnishing or the visibility of tracer filled balloons in deflated state. In this contribution, we present for the first time a balloon catheter that is molded from a granulate incorporating nanoparticles and can be visualized sufficiently in MPI. Computed tomography is used to show the homogeneous distribution of particles within the material. Safety measurements confirm that the incorporation of nanoparticles has no negative effect on the balloon. A dynamic experiment is performed to show that the inflation as well as deflation of the balloon can be imaged with MPI.
UR - http://www.scopus.com/inward/record.url?scp=85132750909&partnerID=8YFLogxK
U2 - 10.1109/TMI.2022.3183948
DO - 10.1109/TMI.2022.3183948
M3 - Journal articles
C2 - 35709119
AN - SCOPUS:85132750909
SN - 0278-0062
VL - 41
SP - 3301
EP - 3308
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 11
ER -