First case of disseminated cryptococcosis in a Gorilla gorilla

Alexander Mischnik*, Julia Stockklausner, Nicole Hohneder, Henrik E. Jensen, Stefan Zimmermann, David E. Reuss, Volker Rickerts, Kathrin Tintelnot, Clemens Stockklausner

*Corresponding author for this work
2 Citations (Scopus)


Summary: In humans, Cryptococcus mainly infects individuals with HIV infection or other types of immunosuppression. Here, we report the first case of disseminated cryptococcosis in a simian immunodeficiency virus-negative 27-year-old female Gorilla gorilla presenting with lethargy, progressive weight loss and productive cough. The diagnosis was confirmed by positive lung biopsy culture, serum cryptococcal antigen, and cerebral histopathology demonstrating encapsulated yeasts. Molecular characterisation of lung culture isolate yielded Cryptococcus neoformans var. grubii. An immune-deficiency could not be demonstrated.

Original languageEnglish
Issue number11
Pages (from-to)664-671
Number of pages8
Publication statusPublished - 01.11.2014

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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