Abstract
The molecular mechanisms explaining why relapses of inflammatory arthritis occur at previously affected sites are unknown. In this issue of Immunity, Friščić et al. propose that local fibroblasts perpetuate inflammation after priming through cell-intrinsic complement C3, which reprograms their bioenergetics and activates the inflammasome.
Original language | English |
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Journal | Immunity |
Volume | 54 |
Issue number | 5 |
Pages (from-to) | 847-850 |
Number of pages | 4 |
ISSN | 1074-7613 |
DOIs | |
Publication status | Published - 11.05.2021 |
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)