Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber; J. Galle; P. L. Chiodini; J. Rupp; R. Birke; E. Vollmer; P. Zabel; C. Lange

doi:10.1007/s15010-005-5060-x

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

H. P. Hauber
, J. Galle
, P. L. Chiodini
, J. Rupp
, R. Birke
, E. Vollmer
, P. Zabel
, C. Lange^*

^*Corresponding author for this work

Airway Research Center North
University of London

46 Citations (Scopus)

Abstract

We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

Original language	English
Journal	Infection
Volume	33
Issue number	5-6
Pages (from-to)	383-386
Number of pages	4
ISSN	0300-8126
DOIs	https://doi.org/10.1007/s15010-005-5060-x
Publication status	Published - 01.10.2005

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

Access to Document

10.1007/s15010-005-5060-x

Cite this

@article{e7d6638d69ae447fab1002a57bbdfc5a,

title = "Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin",

abstract = "We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.",

author = "Hauber, \{H. P.\} and J. Galle and Chiodini, \{P. L.\} and J. Rupp and R. Birke and E. Vollmer and P. Zabel and C. Lange",

year = "2005",

month = oct,

day = "1",

doi = "10.1007/s15010-005-5060-x",

language = "English",

volume = "33",

pages = "383--386",

journal = "Infection",

issn = "0300-8126",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "5-6",

}

TY - JOUR

T1 - Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

AU - Hauber, H. P.

AU - Galle, J.

AU - Chiodini, P. L.

AU - Rupp, J.

AU - Birke, R.

AU - Vollmer, E.

AU - Zabel, P.

AU - Lange, C.

PY - 2005/10/1

Y1 - 2005/10/1

N2 - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

AB - We report the case of a 77-year-oLd man who developed a Strongyloides hyperinfection syndrome following immunosuppressive therapy more than 60 years after he moved away from an area endemic for Strongyloides stercoralis. Successful eradication of the nematode was achieved with an off label subcutaneous formulation of ivermectin. However, the patient subsequently died from acute respiratory distress syndrome (ARDS). Despite a high wormload in the stool and sputum of the patient and delayed infection control measures in the hospital, testing of the medical staff revealed a very low risk of Strongyloides transmission among healthcare workers.

UR - https://www.scopus.com/pages/publications/27644548042

U2 - 10.1007/s15010-005-5060-x

DO - 10.1007/s15010-005-5060-x

M3 - Journal articles

C2 - 16258873

AN - SCOPUS:27644548042

SN - 0300-8126

VL - 33

SP - 383

EP - 386

JO - Infection

JF - Infection

IS - 5-6

ER -

Fatal outcome of a hyperinfection syndrome despite successful eradication of Strongyloides with subcutaneous ivermectin

Abstract

UN SDGs

Research Areas and Centers

Access to Document

Other files and links

Fingerprint

Cite this