Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

J. Hagenah; C. Klein; M. Sieberer; P. Vieregge

doi:10.1007/s007020050159

Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

J. Hagenah, C. Klein, M. Sieberer, P. Vieregge^*

^*Corresponding author for this work

9 Citations (Scopus)

Abstract

We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

Original language	English
Journal	Journal of Neural Transmission
Volume	106
Issue number	3-4
Pages (from-to)	301-307
Number of pages	7
ISSN	0300-9564
DOIs	https://doi.org/10.1007/s007020050159
Publication status	Published - 06.05.1999

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SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

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10.1007/s007020050159

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abstract = "We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.",

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AU - Hagenah, J.

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AU - Vieregge, P.

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N2 - We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

AB - We report three women between 80 and 87 years of age who had longstanding essential tremor. Due to an erroneous diagnosis of Parkinsonism they had received levodopa preparations for 13, 16 and 25 years, respectively, with cumulative levodopa equivalent doses of 18.0, 9.0, and 4.1 kg. The patients showed neither dyskinesias nor signs of Parkinsonism. These observations do not support a detrimental role of chronic levodopa exposure in elderly individuals with essential tremor.

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Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: Further clinical evidence

Abstract

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