Evaluation and Comparison of Force Terms for the Estimation of Lung Motion by Non-Linear Registration of 4D-CT Image Data

Alexander Schmidt-Richberg, J. Ehrhardt, R. Werner, H. Handels

Abstract

The estimation of respiratory lung motion is a basic precondition for the analysis of breathing dynamics and its impact on radiotherapeutic treatment of lung tumors. For this purpose, a common approach is to perform a non-linear registration of the time frames of 4D image data. In this work, we present an evaluation study of different distance measures and force terms respectively that are used for the registration of thoracic CT images. Hereby, we focus on comparing force terms related to Thirion's demons registration with forces derived from the Sum of Squared Differences (SSD). We show that Thirion-based forces generally outperform the SSD term with respect to target registration error (TRE). For the majority of the tested image data, active demon forces provide the best results for the registration of thoracic CT images.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany
Number of pages4
Volume25/4
Place of PublicationBerlin, Heidelberg
PublisherSpringer Verlag
Publication date01.12.2009
Pages2128-2131
ISBN (Print)978-3-642-03881-5
ISBN (Electronic)978-3-642-03882-2
DOIs
Publication statusPublished - 01.12.2009
EventWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging - Munich , Germany
Duration: 07.09.200912.09.2009
Conference number: 81644

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