Erhöhte Mortalität bei Schwerbrandverletzten mit Hypernatriämie

Translated title of the contribution: Increased mortality in hypernatremic burned patients

Thomas Namdar*, Frank Siemers, Peter L. Stollwerck, Felix H. Stang, Peter Mailänder, Thomas Lange

*Corresponding author for this work
7 Citations (Scopus)


Introduction: In-hospital hypernatremia develops usually iatrogenically from inadequate or inappropriate fluid prescription. In severely burned patient an extensive initial fluid resuscitation is necessary for burn shock survival. After recovering of cellular integrity the circulating volume has to be normalized. Hereby extensive water and electrolyte shifts can provoke hypernatremia. Purpose: Is a hypernatremic state associated with increased mortality? Method: Retrospective study for the incidence of hypernatremia and survival in 40 patients with a totally burned surface area (TBSA) >10%. Age, sex, TBSA, ABSI-Score and fluid resuscitation within the first 24 hours were analyzed. Patients were separated in two groups without (Group A) or with (Group B) hypernatremia. Results: Hypernatremia occurred on day 5±1.4. No significant difference for age, sex, TBSA, ABSI-Score and fluid resuscitation within the first 24 hours were calculated. In Group A all patients survived, while 3 of the hypernatremic patient in Group B died during ICU-stay (Odds-ratio = 1.25; 95% CI 0.971-1.61; p=0.046). Conclusion: Burned patients with an in-hospital acquired hypernatremia have an increased mortality risk. In case of a hypernatremic state early intervention is obligatory. There is a need of a fluid removal strategy in severely burned patient to avoid water imbalance.

Translated title of the contributionIncreased mortality in hypernatremic burned patients
Original languageGerman
JournalGMS German Medical Science
Publication statusPublished - 07.06.2010


Dive into the research topics of 'Increased mortality in hypernatremic burned patients'. Together they form a unique fingerprint.

Cite this