Erfolgreiche therapie des IgA-pemphigus vom subkorneal pustulösen typ

Translated title of the contribution: Successful treatment of subcorneal pustular type of IgA pemphigus

U. Raap*, B. Völker, H. Petering, T. Hashimoto, D. Zillikens, A. Kapp, T. Werfel

*Corresponding author for this work
2 Citations (Scopus)


IgA pemphigus is a rare autoimmune intraepidermal blistering disease characterized by in vivo bound, and circulating IgA autoantibodies that target cell surface components (cadherins) of epidermal keratinocytes. The average age of onset is approximately 50 years. Histological hallmarks of IgA pemphigus are epidermal acantholysis, subcorneal or intraepidermal pustulosis, and neutrophilic infiltration. The main clinical characteristics are erythematous skin lesions with vesiculopustules, erosions, crusts and desquamation, favoring the trunk, groins, axillaries, and proximal extremities. The drug of choice for treating IgA pemphigus is diaminodiphenylsulfone. In this case study, we describe a patient who suffered from IgA pemphigus and responded well to diaminodiphenylsulfone.

Translated title of the contributionSuccessful treatment of subcorneal pustular type of IgA pemphigus
Original languageGerman
Issue number1
Pages (from-to)66-70
Number of pages5
Publication statusPublished - 01.2005


Dive into the research topics of 'Successful treatment of subcorneal pustular type of IgA pemphigus'. Together they form a unique fingerprint.

Cite this