Entwicklungstrajektorien der sensomotorischen und kognitiven Kontrolle beim Gilles de la Tourette Syndrom

The relationship between tics and preceding urges in Tourette syndrome suggests that abnormal internal monitoring is refl ected in abnormal perceptual, attentional, and response selection. This article uses the theory of event coding to conceptualize Tourette syndrome as a disorder of the integration of perception and action. Given that Tourette syndrome is a prototypical neurodevelopmental disorder with a characteristic clinical course in childhood and early adolescence, we focus on reviewing developmental trajectories of perception-action binding and their neural correlates in Tourette and healthy controls with a view toward the dopaminergic system. Future cross-sectional and longitudinal research systematically comparing typical development and Tourette-related alterations of neurophysiological correlates underlying perception- A ction binding may shed light on individual differences in the clinical course in adolescence and adulthood.