TY - CONF
T1 - Endo-microscopic optical coherence tomography (emOCT) with dynamic contrast
AU - Schulz-Hildebrandt, Hinnerk
AU - Ahrens, Martin
AU - Münter, Michael
AU - Wilken, Elisa
AU - Kohlfärber, Tabea
AU - Holzhausen, Cornelia
AU - König, Peter
AU - Hüttmann, Gereon
PY - 2021/8/24
Y1 - 2021/8/24
N2 - Here we present a forward-looking endoscope for dynamic microscopic OCT reaching a lateral resolution of 1.3 µm and 0.8 mm field of view. Since tissue motion degrades dynamic imaging, tissue was immobilized by suction. The endoscope was placed in a 4 mm stainless-steel sheath, which was connected to a vacuum pump. In mice, the endoscope can access various inner organs using open surgery or laparoscopy. The potential of the dynamic endo-microscopic OCT was demonstrated on relevant murine tissue such as liver, spleen and kidney. Otherwise invisible cellular and subcellular structures were imaged by dynamic mOCT with high contrast.
AB - Here we present a forward-looking endoscope for dynamic microscopic OCT reaching a lateral resolution of 1.3 µm and 0.8 mm field of view. Since tissue motion degrades dynamic imaging, tissue was immobilized by suction. The endoscope was placed in a 4 mm stainless-steel sheath, which was connected to a vacuum pump. In mice, the endoscope can access various inner organs using open surgery or laparoscopy. The potential of the dynamic endo-microscopic OCT was demonstrated on relevant murine tissue such as liver, spleen and kidney. Otherwise invisible cellular and subcellular structures were imaged by dynamic mOCT with high contrast.
UR - https://www.mendeley.com/catalogue/590af0bc-dd7a-3745-b72d-576bdff399a4/
UR - https://www.mendeley.com/catalogue/590af0bc-dd7a-3745-b72d-576bdff399a4/
U2 - 10.1117/12.2575733
DO - 10.1117/12.2575733
M3 - Conference Papers
ER -
