Emergence of Low-level Delamanid and Bedaquiline Resistance during Extremely Drug-resistant Tuberculosis Treatment

Silke Polsfuss*, Sabine Hofmann-Thiel, Matthias Merker, David Krieger, Stefan Niemann, Holger Rüssmann, Nicolas Schönfeld, Harald Hoffmann, Katharina Kranzer

*Corresponding author for this work
14 Citations (Scopus)

Abstract

Two new drugs, delamanid and bedaquiline, have recently been approved for treatment of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis. Here, we report a case of clofazimine, bedaquiline, and low-level delamanid resistances acquired during treatment of a patient with XDR tuberculosis.

Original languageEnglish
JournalClinical Infectious Diseases
Volume69
Issue number7
Pages (from-to)1229-1231
Number of pages3
ISSN1058-4838
DOIs
Publication statusPublished - 13.09.2019

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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