Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla(OXA-244) in Germany, 2019 to 2020.

Sybille Welker; Sébastien Boutin; Thomas Miethke; Klaus Heeg; Dennis Nurjadi

Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla(OXA-244) in Germany, 2019 to 2020.

Sybille Welker, Sébastien Boutin, Thomas Miethke, Klaus Heeg, Dennis Nurjadi

Institute of Medical Microbiology

Translational Lung Research Center Heidelberg (TLRC)

Abstract

The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.

Original language	English
Journal	Eurosurveillance
Issue number	46
Publication status	Published - 01.11.2020

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title = "Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla(OXA-244) in Germany, 2019 to 2020.",

abstract = "The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.",

author = "Sybille Welker and S{\'e}bastien Boutin and Thomas Miethke and Klaus Heeg and Dennis Nurjadi",

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T1 - Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla(OXA-244) in Germany, 2019 to 2020.

AU - Welker, Sybille

AU - Boutin, Sébastien

AU - Miethke, Thomas

AU - Heeg, Klaus

AU - Nurjadi, Dennis

N1 - Place: Sweden

PY - 2020/11/1

Y1 - 2020/11/1

N2 - The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.

AB - The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.

M3 - Journal articles

JO - Eurosurveillance

JF - Eurosurveillance

IS - 46

ER -

Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla(OXA-244) in Germany, 2019 to 2020.

Abstract

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