Embryos refrozen-thawed by vitrification lead to live births: Case report

Ana L. Mauri; Claudia G. Petersen; João B.A. Oliveira; Ricardo L.R. Baruffi; Saffa Al-Hasani; José G. Franco

doi:10.1016/j.mefs.2010.09.008

Embryos refrozen-thawed by vitrification lead to live births: Case report

Ana L. Mauri, Claudia G. Petersen, João B.A. Oliveira, Ricardo L.R. Baruffi, Saffa Al-Hasani, José G. Franco^*

^*Corresponding author for this work

Clinic of Gynecology and Obstetrics

2 Citations (Scopus)

Abstract

Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular.

Original language	English
Journal	Middle East Fertility Society Journal
Volume	16
Issue number	1
Pages (from-to)	93-97
Number of pages	5
ISSN	1110-5690
DOIs	https://doi.org/10.1016/j.mefs.2010.09.008
Publication status	Published - 01.01.2011

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title = "Embryos refrozen-thawed by vitrification lead to live births: Case report",

abstract = "Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular.",

author = "Mauri, {Ana L.} and Petersen, {Claudia G.} and Oliveira, {Jo{\~a}o B.A.} and Baruffi, {Ricardo L.R.} and Saffa Al-Hasani and Franco, {Jos{\'e} G.}",

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doi = "10.1016/j.mefs.2010.09.008",

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T1 - Embryos refrozen-thawed by vitrification lead to live births: Case report

AU - Mauri, Ana L.

AU - Petersen, Claudia G.

AU - Oliveira, João B.A.

AU - Baruffi, Ricardo L.R.

AU - Al-Hasani, Saffa

AU - Franco, José G.

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular.

AB - Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular.

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Embryos refrozen-thawed by vitrification lead to live births: Case report

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