Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of DPC4 Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Hendrik Ungefroren*, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Tobias Keck, Jens Uwe Marquardt

*Corresponding author for this work

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related mortality worldwide, with a 5-year-survival rate below 10% that is the lowest of all cancer types [...].

Original languageEnglish
Article number581
JournalCancers
Volume15
Issue number3
ISSN2072-6694
DOIs
Publication statusPublished - 18.01.2023

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