Einschätzungen der Präimplantationsdiagnostik - Abhängigkeit von eigenen Erfahrungen

Purpose: The aim of the study was to gain data about the attitudes of different groups towards preimplantation genetic diagnosis (PGD). With the help of a questionnaire we evaluated the acceptance of PGD and pregnancy termination in Germany in different population groups. Patients and Methods: 34 infertile patients, 74 patients who asked for PGD, 29 women, who had finished family planning, and 59 medical students were asked for their opinion in a standardized and closed questionnaire. Results: All groups, with the exception of the students, were very positive towards PGD. The PGD- and infertility-patients found PGD more acceptable than pregnancy termination after prenatal diagnosis. All groups perceived the main advantage of PGD to be that pregnancy terminations due to genetic abnormalities can be avoided. Only the students saw a difficulty in the wastage of embryos and would have problems to waste an embryo with a genetic defect. 90.6% of the infertility patients, 78.1% of the PGD-patients, 72.1% of women with finished family planning and 53.7% of the students support the option of PGD for aneuploidies in IVF therapy. Conclusion: In conclusion, this German cohort recognizes the advantages of PGD, but it is apparent how opinions regarding this technique are influenced by the individual situation and experiences.