Effectiveness and toxicity of single-fraction radiotherapy with 1x8 Gy for metastatic spinal cord compression

Dirk Rades*, Lukas J.A. Stalpers, Maarten C.C.M. Hulshof, Oliver Zschenker, Winfried Alberti, Caro C.E. Koning

*Corresponding author for this work
21 Citations (Scopus)

Abstract

Toxicity and functional outcome were evaluated in 199 MSCC-patients irradiated with 1×8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (≥12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory.

Original languageEnglish
JournalRadiotherapy and Oncology
Volume75
Issue number1
Pages (from-to)70-73
Number of pages4
ISSN0167-8140
DOIs
Publication statusPublished - 2005

Fingerprint

Dive into the research topics of 'Effectiveness and toxicity of single-fraction radiotherapy with 1x8 Gy for metastatic spinal cord compression'. Together they form a unique fingerprint.

Cite this