TY - JOUR
T1 - Effectiveness and toxicity of single-fraction radiotherapy with 1x8 Gy for metastatic spinal cord compression
AU - Rades, Dirk
AU - Stalpers, Lukas J.A.
AU - Hulshof, Maarten C.C.M.
AU - Zschenker, Oliver
AU - Alberti, Winfried
AU - Koning, Caro C.E.
N1 - Funding Information:
The authors would like to thank Mrs M. van der Kar for her assistance in logistics and organisation. This project was supported by the ESTRO (EDRO Technology Transfer Grant).
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - Toxicity and functional outcome were evaluated in 199 MSCC-patients irradiated with 1×8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (≥12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory.
AB - Toxicity and functional outcome were evaluated in 199 MSCC-patients irradiated with 1×8 Gy. Motor function improved in 54/199 patients (27%). Patients who regained walking ability were 20/78 (26%). Long-term-survivors (≥12 months) who needed re-irradiation for in-field-recurrence were 19/65 (29%). Acute toxicity was mild, late toxicity not observed. A randomised trial comparing single-fraction RT to multi-fraction RT is mandatory.
UR - http://www.scopus.com/inward/record.url?scp=18144377397&partnerID=8YFLogxK
U2 - 10.1016/j.radonc.2004.12.013
DO - 10.1016/j.radonc.2004.12.013
M3 - Journal articles
C2 - 15878103
AN - SCOPUS:18144377397
VL - 75
SP - 70
EP - 73
JO - Radiotherapy and Oncology
JF - Radiotherapy and Oncology
SN - 0167-8140
IS - 1
ER -
