Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Jürgen Eggers; Björn Koch; Karsten Meyer; Inke König; Günter Scidel

doi:10.1002/ana.10590

Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Jürgen Eggers, Björn Koch, Karsten Meyer, Inke König, Günter Scidel^*

^*Corresponding author for this work

148 Citations (Scopus)

Abstract

We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

Original language	English
Journal	Annals of Neurology
Volume	53
Issue number	6
Pages (from-to)	797-800
Number of pages	4
ISSN	0364-5134
DOIs	https://doi.org/10.1002/ana.10590
Publication status	Published - 01.06.2003

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10.1002/ana.10590

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abstract = "We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.",

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AU - Eggers, Jürgen

AU - Koch, Björn

AU - Meyer, Karsten

AU - König, Inke

AU - Scidel, Günter

PY - 2003/6/1

Y1 - 2003/6/1

N2 - We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

AB - We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue-type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C-US) over 1 hour; 14 patients were selected for the control group. The C-US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C-US group (Barthel index, p = 0.037) after 3 months.

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ER -

Effect of ultrasound on thrombolysis of middle cerebral artery occlusion

Abstract

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