Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs)

Ankit Malhotra, Felix Spieß, Corinna Stegelmeier, Christina Debbeler, Kerstin Lüdtke-Buzug

Abstract

There are various methods to synthesize superparamagnetic nanoparticles (SPIONs) useful for MPI (magnetic particle imaging) and in therapy (Hypothermia) such as co-precipitation, hydrothermal reactions etc. In this research, the focus is to analyse the effects of crucial parameters such as effect of molecular mass of dextran and temperature of the co-precipitation. These parameters play a crucial role in the inherent magnetic properties of the resulting SPIONs. The amplitude spectrum and hysteresis curve of the SPIONs is analysed with MPS (magnetic particle spectrometer). PCCS (photon cross-correlation spectroscopy) measurements are done to analyse the size distribution of hydrodynamic diameter the resulting SPIONs.
Original languageEnglish
JournalCurrent Directions in Biomedical Engineering
Volume2
Issue number1
Pages (from-to)529-532
Number of pages4
ISSN2364-5504
DOIs
Publication statusPublished - 30.09.2016

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