ECG changes after percutaneous edge-to-edge mitral valve repair

Hou Bo; David Heinzmann; Christian Grasshoff; Peter Rosenberger; Christian Schlensak; Meinrad Gawaz; Jürgen Schreieck; Harald F. Langer; Johannes Patzelt; Peter Seizer

doi:10.1002/clc.23258

ECG changes after percutaneous edge-to-edge mitral valve repair

Hou Bo, David Heinzmann, Christian Grasshoff, Peter Rosenberger, Christian Schlensak, Meinrad Gawaz, Jürgen Schreieck, Harald F. Langer, Johannes Patzelt, Peter Seizer^*

^*Corresponding author for this work

Department of Internal Medicine II

University of Tubingen

5 Citations (Scopus)

Abstract

Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.

Original language	English
Journal	Clinical Cardiology
Volume	42
Issue number	11
Pages (from-to)	1094-1099
Number of pages	6
ISSN	0160-9289
DOIs	https://doi.org/10.1002/clc.23258
Publication status	Published - 01.11.2019

Funding

This study was supported by grants from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, TRR 240 and KFO 274), the Volkswagen foundation (Lichtenberg program), the Deutsche Herzstiftung, and by the research fund of “Sonderlinie Hochschulmedizin” an initiative of the Ministry of Science, Research and Arts, Baden‐Württemberg, Germany.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1002/clc.23258

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@article{40bd31f644ca4c7099557f56e0a06585,

title = "ECG changes after percutaneous edge-to-edge mitral valve repair",

abstract = "Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.",

author = "Hou Bo and David Heinzmann and Christian Grasshoff and Peter Rosenberger and Christian Schlensak and Meinrad Gawaz and J{\"u}rgen Schreieck and Langer, \{Harald F.\} and Johannes Patzelt and Peter Seizer",

note = "Funding Information: This study was supported by grants from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, TRR 240 and KFO 274), the Volkswagen foundation (Lichtenberg program), the Deutsche Herzstiftung, and by the research fund of “Sonderlinie Hochschulmedizin” an initiative of the Ministry of Science, Research and Arts, Baden‐W{\"u}rttemberg, Germany. Publisher Copyright: {\textcopyright} 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

year = "2019",

month = nov,

day = "1",

doi = "10.1002/clc.23258",

language = "English",

volume = "42",

pages = "1094--1099",

journal = "Clinical Cardiology",

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TY - JOUR

T1 - ECG changes after percutaneous edge-to-edge mitral valve repair

AU - Bo, Hou

AU - Heinzmann, David

AU - Grasshoff, Christian

AU - Rosenberger, Peter

AU - Schlensak, Christian

AU - Gawaz, Meinrad

AU - Schreieck, Jürgen

AU - Langer, Harald F.

AU - Patzelt, Johannes

AU - Seizer, Peter

N1 - Funding Information: This study was supported by grants from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, TRR 240 and KFO 274), the Volkswagen foundation (Lichtenberg program), the Deutsche Herzstiftung, and by the research fund of “Sonderlinie Hochschulmedizin” an initiative of the Ministry of Science, Research and Arts, Baden‐Württemberg, Germany. Publisher Copyright: © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.

AB - Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.

UR - https://www.scopus.com/pages/publications/85073934847

U2 - 10.1002/clc.23258

DO - 10.1002/clc.23258

M3 - Journal articles

C2 - 31497886

AN - SCOPUS:85073934847

SN - 0160-9289

VL - 42

SP - 1094

EP - 1099

JO - Clinical Cardiology

JF - Clinical Cardiology

IS - 11

ER -

ECG changes after percutaneous edge-to-edge mitral valve repair

Abstract

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UN SDGs

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