TY - JOUR
T1 - ECG changes after percutaneous edge-to-edge mitral valve repair
AU - Bo, Hou
AU - Heinzmann, David
AU - Grasshoff, Christian
AU - Rosenberger, Peter
AU - Schlensak, Christian
AU - Gawaz, Meinrad
AU - Schreieck, Jürgen
AU - Langer, Harald F.
AU - Patzelt, Johannes
AU - Seizer, Peter
N1 - Funding Information:
This study was supported by grants from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, TRR 240 and KFO 274), the Volkswagen foundation (Lichtenberg program), the Deutsche Herzstiftung, and by the research fund of “Sonderlinie Hochschulmedizin” an initiative of the Ministry of Science, Research and Arts, Baden‐Württemberg, Germany.
Publisher Copyright:
© 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.
AB - Background: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. Hypothesis: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. Methods: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up. Results: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P <.05, respectively). Conclusion: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.
UR - http://www.scopus.com/inward/record.url?scp=85073934847&partnerID=8YFLogxK
U2 - 10.1002/clc.23258
DO - 10.1002/clc.23258
M3 - Journal articles
C2 - 31497886
AN - SCOPUS:85073934847
SN - 0160-9289
VL - 42
SP - 1094
EP - 1099
JO - Clinical Cardiology
JF - Clinical Cardiology
IS - 11
ER -
