Does erythropoietin protect the preterm brain?

T. Strunk, C. Härtel, C. Schultz*

*Corresponding author for this work
14 Citations (Scopus)


There is a high incidence of hypoxic-ischaemic brain injury and intraventricular haemorrhage in newborn infants, particularly those born preterm. Many die during the newborn period or suffer permanent neurodevelopmental handicaps. Hypoxic brain injury develops over several hours and could potentially be influenced by intervention. At present, no drug exists that effectively prevents infant brain injury or ameliorates detrimental neurodevelopmental effects. The hypothesis is put forward that systemic administration of recombinant human erythropoietin positively affects the neurodevelopmental outcome of high risk preterm infants affected by brain injury. A multicentre, randomised, placebo controlled study is proposed to prospectively test this hypothesis.

Original languageEnglish
JournalArchives of Disease in Childhood: Fetal and Neonatal Edition
Issue number4
Pages (from-to)F364-F366
Publication statusPublished - 07.2004

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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