Abstract
An HSR in chromosome 1 which is found in many feral populations of Mus musculus domesticus was shown in previous studies to consist of a high-copy long-range repeat cluster. One such cluster, MUT, showed distorted transmission ratios when introduced by female parents. MUT/+ offspring were preferentially recovered at the expense of +/+ embryos in the progeny of ♀ MUT/+ x ♂ +/+ but were found at the expected 1:1 ratio in reciprocal crosses. Preferential recovery of maternal MUT was due to lethality of postimplantation +/+ embryos. There was no distortion of the recovery ratio in MUT/+ x MUT/MUT progeny: maternal MUT and + clusters were present among live implants at a 1:1 ratio. Maternal and zygotic effects therefore contribute to the phenomenon. The mechanism of their interaction is unknown.
| Original language | English |
|---|---|
| Journal | Genetical Research |
| Volume | 68 |
| Issue number | 2 |
| Pages (from-to) | 125-129 |
| Number of pages | 5 |
| ISSN | 0016-6723 |
| DOIs | |
| Publication status | Published - 10.1996 |
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)