Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

A. Rody*, T. Karn, E. Ruckhaeberle, L. Hanker, R. Gaetje, U. Holtrich, M. Kaufmann

*Corresponding author for this work

Abstract

Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. This analysis reveals two breast cancer subgroups with stem cell-like features, differing in ER-status and proliferation as well as in their clinical course of disease.

Original languageEnglish
JournalEuropean Journal of Cancer
Volume44
Issue number13
Pages (from-to)1789-1792
Number of pages4
ISSN0959-8049
DOIs
Publication statusPublished - 09.2008

Funding

We thank Samira Adel and Katherina Kourtis for expert technical assistance. This work was supported by grants from the Deutsche Krebshilfe, Bonn, the Margarete Bonifer-Stiftung, Bad Soden, the BANSS-Stiftung, Biedenkopf and the Dr. Robert Pfleger-Stiftung, Bamberg.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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