Diet-induced menstrual irregularities: Effects of age and weight loss

U. Schweiger, R. Laessle, H. Pfister, C. Hoehl, M. Schwingenschloegel, M. Schweiger, K. M. Pirke

54 Citations (Scopus)


Luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), and progesterone (P) levels were followed in 22 healthy, normal-weight women (aged 19 to 30 years) for a control and a diet menstrual cycle. During the diet cycle, they lost weight on a high-carbohydrate, vegetarian, 1000-calorie diet. During the control cycle, luteal phase in 5 subjects failed to meet the criteria: length ≥ 8 days and P maximum ≥ 6 ng/ml; during the diet cycle, the number of subjects who failed to meet these criteria was 14 (chi-square test, P < 0.02). No evidence of follicular phase disturbance was observed during the diet. Age and weight loss significantly changed parameters of the diet luteal phase: length and area under LH, FSH, E2, and P curves. Generally, hormone plasma concentrations during the luteal phase were lower the younger the age and the greater the weight loss.

Original languageEnglish
JournalFertility and Sterility
Issue number5
Pages (from-to)746-751
Number of pages6
Publication statusPublished - 1987

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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