Die PRISCUS-Liste im klinischen Test: Praktikabilität und Vergleich mit internationalen PIM-Listen

Translated title of the contribution: The PRISCUS list in clinical routine: Practicability and comparison to international PIM lists

S. Siebert, B. Elkeles, G. Hempel, J. Kruse, M. Smollich*

*Corresponding author for this work
18 Citations (Scopus)

Abstract

Background: Certain drugs are classified as potentially inappropriate medications (PIM) for the elderly. In 2010, the PRISCUS list was published, specifically designed for its applicability in the German pharmaceutical market. The aim of this study was to evaluate the PRISCUS list compared to international PIM lists. Methods: Based on selected PIM lists (PRISCUS, STOPP/START, Beers), the medications of 308 patients at a clinic of geriatric rehabilitation were screened for PIMs. Applying START criteria, omission of indicated drug therapies was detected. Results: Regarding the rate of PIM detection, the PRISCUS list was less sensitive than the application of STOPP criteria. While hospitalized, the mean number of administered PIMs per patient was 1. 2 based on STOPP criteria and 0. 5 based on the PRISCUS list. The lowest number of PIMs per patient was detected by applying the Beers list (0. 4 PIMs). Conclusion: The Beers list should not be used in the German pharmaceutical market. The amendment of diagnosis-related STOPP criteria to the PRISCUS list would be useful to significantly advance therapeutic success and drug safety in the elderly.

Translated title of the contributionThe PRISCUS list in clinical routine: Practicability and comparison to international PIM lists
Original languageGerman
JournalZeitschrift fur Gerontologie und Geriatrie
Volume46
Issue number1
Pages (from-to)35-47
Number of pages13
ISSN0948-6704
DOIs
Publication statusPublished - 01.2013

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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