Abstract
Underweight is a key symptom in anorexia nervosa. In this review we summarize recent findings pertaining to weight regulation in this eating disorder. The observation that a body mass index below 13 kg/m2 upon admission for inpatient treatment is associated with a high mortality rate and chronic persistence of underweight is of obvious clinical relevance. A lowered leptin secretion, which results from the weight loss, is presumably of major importance for the development of amenorrhea. We discuss findings pertaining to a reduced body weight in other psychiatric disorders during adolescence in the light of Kretschmer's findings related to body frame and psychopathology.
Translated title of the contribution | Body weight regulation in anorexia nervosa under special consideration of leptin secretion |
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Original language | German |
Journal | Nervenarzt |
Volume | 70 |
Issue number | 1 |
Pages (from-to) | 31-40 |
Number of pages | 10 |
ISSN | 0028-2804 |
DOIs | |
Publication status | Published - 01.1999 |