Dependence of serum erythropoietin level on erythropoiesis in leukemia.

W. Jelkmann; H. Johannsen; G. Wiedemann; M. Otte; T. Wagner

doi:10.1007/978-3-642-74643-7_15

Dependence of serum erythropoietin level on erythropoiesis in leukemia.

W. Jelkmann^*, H. Johannsen, G. Wiedemann, M. Otte, T. Wagner

^*Corresponding author for this work

Institute of Physiology

1 Citation (Scopus)

Abstract

The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.

Original language	English
Journal	Haematology and blood transfusion
Volume	33
Pages (from-to)	83-86
Number of pages	4
ISSN	0171-7111
DOIs	https://doi.org/10.1007/978-3-642-74643-7_15
Publication status	Published - 1990

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

Access to Document

10.1007/978-3-642-74643-7_15

Cite this

@article{299032d8b0ec4eaf8e09c1dbefd7c6e1,

title = "Dependence of serum erythropoietin level on erythropoiesis in leukemia.",

abstract = "The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.",

author = "W. Jelkmann and H. Johannsen and G. Wiedemann and M. Otte and T. Wagner",

note = "Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine",

year = "1990",

doi = "10.1007/978-3-642-74643-7\_15",

language = "English",

volume = "33",

pages = "83--86",

journal = "Haematology and blood transfusion",

issn = "0171-7111",

}

TY - JOUR

T1 - Dependence of serum erythropoietin level on erythropoiesis in leukemia.

AU - Jelkmann, W.

AU - Johannsen, H.

AU - Wiedemann, G.

AU - Otte, M.

AU - Wagner, T.

N1 - Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine

PY - 1990

Y1 - 1990

N2 - The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.

AB - The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.

UR - https://www.scopus.com/pages/publications/0025110774

U2 - 10.1007/978-3-642-74643-7_15

DO - 10.1007/978-3-642-74643-7_15

M3 - Journal articles

C2 - 2323676

AN - SCOPUS:0025110774

SN - 0171-7111

VL - 33

SP - 83

EP - 86

JO - Haematology and blood transfusion

JF - Haematology and blood transfusion

ER -

Dependence of serum erythropoietin level on erythropoiesis in leukemia.

Abstract

UN SDGs

Research Areas and Centers

Access to Document

Other files and links

Fingerprint

Cite this