TY - JOUR
T1 - Dependence of serum erythropoietin level on erythropoiesis in leukemia.
AU - Jelkmann, W.
AU - Johannsen, H.
AU - Wiedemann, G.
AU - Otte, M.
AU - Wagner, T.
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 1990
Y1 - 1990
N2 - The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.
AB - The dependence of the serum erythropoietin (Epo) level on the blood hemoglobin concentration was compared in patients suffering from leukemia and ulcerative colitis. In leukemia, the level of immunoreactive and bioactive Epo was generally much higher than in ulcerative colitis at comparable degrees of anemia. The highest Epo values were found in patients with severe bone marrow insufficiency of erythropoiesis. These findings support the hypothesis that the plasma level of Epo depends not only on the hemoglobin concentration of the blood but is also influenced by the proliferative activity of the erythron.
UR - http://www.scopus.com/inward/record.url?scp=0025110774&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-74643-7_15
DO - 10.1007/978-3-642-74643-7_15
M3 - Journal articles
C2 - 2323676
AN - SCOPUS:0025110774
SN - 0171-7111
VL - 33
SP - 83
EP - 86
JO - Haematology and blood transfusion
JF - Haematology and blood transfusion
ER -
