Das Harnblasenkarzinomrezidiv nach BCG-Instillationstherapie. Lokale Therapieoptionen?

Translated title of the contribution: Recurrent bladder cancer after BCG instillation therapy. Local therapy options?

J. M. Laturnus*, D. Jocham, M. Sommerauer

*Corresponding author for this work
1 Citation (Scopus)

Abstract

Patients with a so-called BCG failure (Bacillus Calmette-Guérin) constitute an inhomo-geneous group of patients. Patients with BCG recurrence or BCG refractive tumors are real BCG failures. Therapeutic options are radical cystectomy and a conservative approach, depending on the individual risk of recurrence and progression. Intravesical chemotherapy with docetaxel or gemcitabine after BCG failure shows some promise whereas second line immunotherapy, the combination of BCG and interferon (INF)-α, is an effective regimen but results need to be confirmed. Device-assisted intravesical strategies, such as mitomycin-EMDA or chemohyperthermia are candidates to keep in mind for the near future. Finally, cystectomy results in the best disease-specific survival in patients with BCG failure.

Translated title of the contributionRecurrent bladder cancer after BCG instillation therapy. Local therapy options?
Original languageGerman
JournalUrologe - Ausgabe A
Volume51
Issue number9
Pages (from-to)1209-1219
Number of pages11
ISSN0340-2592
DOIs
Publication statusPublished - 09.2012

Research Areas and Centers

  • Research Area: Luebeck Integrated Oncology Network (LION)

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