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CYP7A1: A Liver Circadian Clock Output Mediating the Metabolic Effects of Sleep Disruption

Henrik Oster*

*Corresponding author for this work
1   Link opens in a new tab Citation (Scopus)

Abstract

All higher animals on this planet show some form of sleep-like behavior, but still a consensus has not been reached on what determines the evolutionary value of sleep. Recent data suggest that one important aspect might be its role in the maintenance of energy homeostasis. Over the past decades, average daily sleep times have decreased by almost 20% in Western societies, in part caused by a largely augmented demand for shift work. In parallel, metabolic disorders such as type-2 diabetes, obesity, and the metabolic syndrome have dramatically increased in prevalence.
Original languageEnglish
JournalCMGH
Volume1
Issue number6
Pages (from-to)574-575
Number of pages2
DOIs
Publication statusPublished - 01.11.2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 2.22-17 Endocrinology, Diabetology, Metabolism
  • 2.23-04 Cognitive, Systems and Behavioural Neurobiology

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  • CRC 654: Plasticity and Sleep

    Born, J. (Speaker), Verleger, R. (Principal Investigator (PI)), Witt, K. (Principal Investigator (PI)), Gais, S. (Principal Investigator (PI)), Kimmig, H. (Principal Investigator (PI)), Backhaus, J. (Principal Investigator (PI)), Junghanns, K. (Principal Investigator (PI)), Marshall, L. (Principal Investigator (PI)), Martinetz, T. (Principal Investigator (PI)), Mölle, M. (Principal Investigator (PI)), Deuschl, G. (Principal Investigator (PI)), Mehdorn, H. M. (Principal Investigator (PI)), Volkmann, J. (Principal Investigator (PI)), Claussen, J. C. (Principal Investigator (PI)), Göder, R. (Principal Investigator (PI)), Anders, S. (Principal Investigator (PI)), Binkofski, F. (Principal Investigator (PI)), Büchel, C. (Principal Investigator (PI)), Ehrlich, I. (Principal Investigator (PI)), Baving, L. (Principal Investigator (PI)), Prehn-Kristensen, A. (Principal Investigator (PI)), Bartsch, T. (Principal Investigator (PI)), Sirota, A. (Principal Investigator (PI)), Münte, T. (Principal Investigator (PI)), Heldmann, M. (Principal Investigator (PI)), Diekelmann, S. (Principal Investigator (PI)), Rauss, K. (Principal Investigator (PI)), Sato, T. (Principal Investigator (PI)), Krägeloh-Mann, I. (Principal Investigator (PI)), Wilke, M. (Principal Investigator (PI)), Hallschmid, M. (Principal Investigator (PI)), Schmid, S. (Principal Investigator (PI)), Kern, W. (Principal Investigator (PI)), Perras, B. (Principal Investigator (PI)), Poets, C. F. (Principal Investigator (PI)), Sayk, F. (Principal Investigator (PI)), Oster, H. (Principal Investigator (PI)), Lehnert, H. (Principal Investigator (PI)), Baier, P. C. (Principal Investigator (PI)), Oltmanns, K. (Principal Investigator (PI)), Fritsche, A. (Principal Investigator (PI)), Preissl, H. (Principal Investigator (PI)), Ernst, M. (Principal Investigator (PI)), Zabel, P. (Principal Investigator (PI)), Solbach, W. (Principal Investigator (PI)), Kalies, K. (Principal Investigator (PI)), Westermann, J. (Principal Investigator (PI)), Rose-John, S. (Principal Investigator (PI)), Lange, T. (Principal Investigator (PI)), Rammensee, H. G. (Principal Investigator (PI)), Autenrieth, S. E. (Principal Investigator (PI)), Köhl, J. (Principal Investigator (PI)) & Ehlers, M. (Principal Investigator (PI))

    01.01.05 → 31.12.17

    Project: DFG Joint Research › DFG Collaborative Research Centers (CRC)

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