Abstract
Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to crystals grown at acidic pH using sodium chloride as the precipitant. However, the growth kinetics differ markedly between the two conditions. The major reason for this is a molecule of MPD that binds tightly in between two lysozyme molecules and favors the growth of the crystals along the crystallographic c direction over growth perpendicular to it.
| Original language | English |
|---|---|
| Journal | Acta Crystallographica Section D: Biological Crystallography |
| Volume | 56 |
| Issue number | 8 |
| Pages (from-to) | 952-958 |
| Number of pages | 7 |
| ISSN | 0907-4449 |
| DOIs | |
| Publication status | Published - 2000 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
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